KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYR
All Species:
24.24
Human Site:
Y467
Identified Species:
66.67
UniProt:
P14679
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14679
NP_000363.1
529
60393
Y467
F
Q
D
Y
I
K
S
Y
L
E
Q
A
S
R
I
Chimpanzee
Pan troglodytes
XP_001136041
529
60377
Y467
F
Q
D
Y
I
K
S
Y
L
E
Q
A
S
R
I
Rhesus Macaque
Macaca mulatta
XP_001105033
530
60113
Y467
F
Q
D
Y
I
K
S
Y
L
E
Q
A
G
R
I
Dog
Lupus familis
XP_542639
548
62116
L490
G
Y
S
Y
A
I
D
L
P
V
E
E
T
P
A
Cat
Felis silvestris
Mouse
Mus musculus
P11344
533
60588
Y467
Y
R
N
Y
I
E
P
Y
L
E
Q
A
S
R
I
Rat
Rattus norvegicus
NP_001101005
530
60340
Y467
Y
R
N
Y
I
E
P
Y
L
E
Q
A
S
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512017
530
59569
F467
F
Q
D
L
I
R
P
F
L
E
Q
A
R
Q
I
Chicken
Gallus gallus
P55024
529
60339
Y467
F
Q
D
F
L
I
P
Y
L
K
Q
A
H
Q
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571088
535
60727
Y469
V
Q
E
F
L
T
P
Y
L
E
Q
A
Q
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96
38.8
N.A.
85.7
87.1
N.A.
74.9
73.5
N.A.
60.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
97.7
57.1
N.A.
92.3
92.2
N.A.
86.4
84.1
N.A.
76.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
66.6
66.6
N.A.
60
53.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
20
N.A.
93.3
93.3
N.A.
80
80
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
0
0
89
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
56
0
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
12
0
0
23
0
0
0
78
12
12
0
0
0
% E
% Phe:
56
0
0
23
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
67
23
0
0
0
0
0
0
0
0
89
% I
% Lys:
0
0
0
0
0
34
0
0
0
12
0
0
0
0
0
% K
% Leu:
0
0
0
12
23
0
0
12
89
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
56
0
12
0
0
0
0
12
0
% P
% Gln:
0
67
0
0
0
0
0
0
0
0
89
0
12
34
0
% Q
% Arg:
0
23
0
0
0
12
0
0
0
0
0
0
12
56
0
% R
% Ser:
0
0
12
0
0
0
34
0
0
0
0
0
45
0
0
% S
% Thr:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
23
12
0
67
0
0
0
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _